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La eleccin del tratamiento ms adecuado debe individualizarse, considerando el estado de salud general, las comorbilidades, las preferencias del paciente y el acompaamiento de un profesional de la salud capacitado

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The control participants did not meet criteria for any psychiatric disorders according to the Structured Clinical Interview for DSM-5 (SCID) conducted by a board-certified psychiatrist

Key point : Modern guidelines stress not ruling out B12 deficiency based solely on normal blood counts

FOXO4-DRI is a D-amino acid retro-inverso peptide that disrupts the intracellular interaction between FOXO4 and p53 in senescent cells, triggering p53-mediated apoptosis selectively in senescent rather than healthy proliferating cells

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